Blood and urine samples

The blood samples you provide will be used to measure things such as kidney, liver, heart function, steroid hormones, and levels of blood sugar and salts in your body. We will also measure levels of BI 690517 in your blood. The study team want to measure these things to assess the effects of the study pills.

The urine samples will be measured for protein markers of kidney disease and damage.

Some of these tests are not routinely performed by all hospitals and ideally all samples need to be measured in a single laboratory, so some of your blood and urine will be transported to Oxford. This is why study blood and urine samples will need to be taken at the study appointments rather than at a different place (such as your GP practice).

The study research team will also ask you if you would allow leftover blood and urine samples, together with your health data collected in this study, to be stored long-term to help investigate other effects of the study medications and other future research (see below).

Leftover blood and urine samples are those which have already been collected for the purposes of the study, and would be discarded otherwise. There is no additional health risk to you. You can choose whether or not you would like to participate in this optional part of the study. If you decide that you do not want to give permission, you can still take part in the main part of the study.